Identification of potential riboswitch elements in Homo Sapiens mRNA 5’UTR sequences using Positive-Unlabeled machine learning

William S. Raymond¹, Jacob DeRoo¹, Brian Munsky^1,2

^{¹ School of Biomedical Engineering, Colorado State University Fort Collins, CO 80523, USA}

^{² Chemical and Biological Engineering, Colorado State University Fort Collins, CO 80523, USA}

A ensemble of 20 positive-unlabeled classifiers was trained on known riboswitch sequences (positive) and human 5’UTR sequences (unlabeled). 5’UTR sequences found by all 20 classifiers to be a riboswitch are displayed for the readers convienence here.

1533 5’UTRs harboring potential riboswitch elements found by one or more classifier of the ensemble are also provided to the reader here

Read the manuscript here

Identification of potential riboswitch elements in Homo Sapiens mRNA 5’UTR sequences using Positive-Unlabeled machine learning

William S. Raymond1, Jacob DeRoo1, Brian Munsky1,2

1 School of Biomedical Engineering, Colorado State University Fort Collins, CO 80523, USA

2 Chemical and Biological Engineering, Colorado State University Fort Collins, CO 80523, USA

William S. Raymond¹, Jacob DeRoo¹, Brian Munsky^1,2

^{¹ School of Biomedical Engineering, Colorado State University Fort Collins, CO 80523, USA}

^{² Chemical and Biological Engineering, Colorado State University Fort Collins, CO 80523, USA}