Detected as a riboswitch by 6 out of 20 classifiers
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5HSAA022142 Similarity: 0.967 Similarity: 0.963 Similarity: 0.963
UTR: 5HSAA022142
Gene: CIRBP
MFE: -53.222
ENS: 0.813
Length: 136.
Predicted Ligands:
cobalamin - 10/20
FMN - 3/20
glycine - 2/20
 RS: URS000231E8B4_1223542
MFE: -53.690
Ligand: cobalamin
Species: Gordonia malaquae NBRC 108250 Cobalamin riboswitch
 RS: URS0000C60C64_414996
MFE: -50.292
Ligand: glycine
Species: Actinopolyspora sp. YIM 90600 Glycine riboswitch
 RS: URS000232E343_564198
MFE: -48.299
Ligand: cobalamin
Species: Mycobacterium bacteremicum Cobalamin riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA022142 URS000231E8B4_1223542 URS0000C60C64_414996 URS000232E343_564198
Length 136. 136. 138. 135.
Similarity - 0.967 0.963 0.963
Ensemble Norm 0.813 - - -
MFE -53.222 -53.690 -50.292 -48.299
Ligands - cobalamin glycine cobalamin
Gene CIRBP - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 6. 5. 8.002
Length SE - 0. 4. 1.
Lev Distance - 42. 42. 45.
UBS 11. 11. 10. 12.
BS 0. 0. 0. 2.
ILL 3. 3. 2. 2.
ILR 4. 4. 3. 4.
H 2. 3. 1. 3.
BL 3. 4. 2. 3.
BR 5. 3. 5. 6.
UN 0.051 0.066 0.058 0.007

Sequences

Field Description
UTR seq + 25 acagaugcaaagcggcaggugugcgcaggugcgugucaacgccacccugggaacccaggauggcugcggacacucacggagcccgcacccaggaacccgcucguagccgccATGGCATCAGATGAAGGCAAACTTT
UTR dot + 25 …(((((…((((((((((((.((..(((.(((((..(((((.(((((….))))).)))).)..))))).)))…)).))))))…………..).)))))….)))))….((((…..))))
RS 1 seq UGUCGCCGGGCUGGCUACGAUUGGCGGCGAACUCGAUGUGGAAGCCGGUGUGAAACCGGCGCGGUCGCGCCACUGUGAGGAUCCGGUGUUCAUUGGCCGGUCCGAGCCAGACCCACGUCGUCAGGCCGAGAAGCCU
RS 1 dot ….(((((((((((((.((.((.(((.(..((((..((((..((((((…..))))))………))))..))))..)))).)).))..))))))))))).))..(((….)))…((((……))))
RS 2 seq UGACGUCAUGCGGGAGAGACUCCGCACUCGGCUCGCGGCAACGCUGCCCGGCCACGGCAAUGGCCCCAACGUGCGCGCGGAGCGCCGAAGGAGCAACACUCCCCACAAACUCUCAGGCCCGAUCACCGCAUGGCACCA
RS 2 dot ….(((((((((((((((((((….((((((((((((.(((.((…(((((……))))).)).))))).)))))…))))).))))……………..))))……..)).)))))))))….
RS 3 seq GACCCCGGGCGUUCCUGCCGCACGGUAGAGUCCGGUUCGACCAGCAGGGGAAUCCGGUGACAAUCCGGAGCUGACGCGCAGCGGUAUGAGGUCUGACCUCGAAGCCCGAAUGCCUGCGGUCGUUGAACCGUCGAC
RS 3 dot ((((.((((((((((((((((((((.(..(((((((((..((….)).))).))))..))..))))….)).)).)))).(((.((((((…))))))..))).))))))))).))))(((((….)))))

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