Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA023591 Similarity: 0.988 Similarity: 0.986 Similarity: 0.986
UTR: 5HSAA023591
Gene: COG1
MFE: -20.388
ENS: 0.992
Length: 61.
Predicted Ligands:
fluoride - 15/20
unknown - 5/20

 RS: URS0000C88432_1452487
MFE: -14.596
Ligand: fluoride
Species: Crenobacter luteus Fluoride riboswitch
 RS: URS0000D81C19_1109412
MFE: -10.332
Ligand: fluoride
Species: Brenneria goodwinii Fluoride riboswitch
 RS: URS0000D668CB_12908
MFE: -18.342
Ligand: unknown
Species: unclassified sequences nhaA-I RNA
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA023591 URS0000C88432_1452487 URS0000D81C19_1109412 URS0000D668CB_12908
Length 61. 62. 61. 61.
Similarity - 0.988 0.986 0.986
Ensemble Norm 0.992 - - -
MFE -20.388 -14.596 -10.332 -18.342
Ligands - fluoride fluoride unknown
Gene COG1 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 10. 2. 5.002
Length SE - 1. 0. 0.
Lev Distance - 12. 18. 17.
UBS 6. 7. 6. 5.
BS 0. 0. 0. 0.
ILL 1. 1. 2. 0.
ILR 0. 0. 0. 1.
H 1. 1. 1. 1.
BL 1. 4. 2. 2.
BR 4. 4. 4. 3.
UN 0.016 0.016 0.033 0.066

Sequences

Field Description
UTR seq + 25 ggcguagguagaucgccgggggcugacgagugcaccATGGCCACCGCGGCAACCTCACCCG
UTR dot + 25 ((.((((((…..((((((((((…………..)))).)).)))).)))).)))).
RS 1 seq CGCAGCGUGGGAGAUGGCAUGCCUCCCUAACCGCCUUUACGGCUGAUGAUGCCUACACGCGA
RS 1 dot (((.(.(((((..((.(((.(((……………..))))).).)).))))).)))).
RS 2 seq GUGCAAAACGGAGAUGACAUUCCUCCAUAACCGCCAUUCGGCUGAUGAUGUCUAUGCACUU
RS 2 dot (((((….(((.((.(((………….(((….))))).).)).))).)))))..
RS 3 seq GGGUGUCGGGUCAACAUAGGGUUGAUCUAGGGCAGGUAAUUGUGUUGGUCGGGCCGCCACG
RS 3 dot .((((((.((((((((((((.(((……..))).)..))))))))))).))).)))…

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