Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA024186 Similarity: 0.959 Similarity: 0.958 Similarity: 0.958
UTR: 5HSAA024186
Gene: COPB2
MFE: -43.068
ENS: 0.997
Length: 155.
Predicted Ligands:
molybdenum - 4/20
FMN - 4/20
glucosamine - 3/20
 RS: URS0000BEEF66_1262823
MFE: -26.918
Ligand: glucosamine
Species: Clostridium sp. CAG:575 glmS glucosamine-6-phosphate activated ribozyme
 RS: URS0000C37002_1768196
MFE: -36.462
Ligand: Mg2+
Species: Erysipelotrichaceae bacterium MTC7 M-box riboswitch (ykoK leader)
 RS: URS0000AB5859_1262853
MFE: -39.007
Ligand: Mg2+
Species: Coprobacillus sp. CAG:183 M-box riboswitch (ykoK leader)
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA024186 URS0000BEEF66_1262823 URS0000C37002_1768196 URS0000AB5859_1262853
Length 155. 155. 155. 155.
Similarity - 0.959 0.958 0.958
Ensemble Norm 0.997 - - -
MFE -43.068 -26.918 -36.462 -39.007
Ligands - glucosamine Mg2+ Mg2+
Gene COPB2 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 9. 5.001 4.009
Length SE - 0. 0. 0.
Lev Distance - 51. 54. 55.
UBS 11. 9. 11. 11.
BS 0. 0. 0. 0.
ILL 4. 5. 3. 5.
ILR 2. 3. 3. 3.
H 3. 2. 4. 4.
BL 1. 2. 2. 1.
BR 4. 3. 3. 3.
UN 0.174 0.194 0.135 0.077

Sequences

Field Description
UTR seq + 25 gacuaucgcgagaaucggcucccggaaguuccacgucagucagucugacggucaguggaucgguggguuuaucucaaggccugaguagccgguaacaaacgaggguucccgggauuggaccgacgcagccATGCCTCTGCGACTTGATATCAAAA
UTR dot + 25 ………((((…(((((((((….((((((((((…..)))))…..))))))))).)))))..))))..((((..(((..((((.(((……..))).)))).))))).))..(((((……..)))))…………..
RS 1 seq GUUUUAUUCCAAGCGCCAGAACCAUUAAUGCAGGUUGACGAGGUCUAGGGUUAUCGAAAUUUCGGCGGAUGCUCUAGUGGCUUUUGCUUAAAGUCAUAAGUAUUGAUACAAAAAAUAAUAGAAAUAUUAAAACAGAAUUCAAUACAUUUAAGCGU
RS 1 dot ……….(((((..(((.((((((..(((..(((.((((((…((….))…)))))).))).)))..)))))).))))))))……….(((((((………(((((….)))))………)))))))……….
RS 2 seq UAGAAAAACCGGUAAGUAAGGUUACUGUAGGGAUACGGGUUGCUGCCGCAAAAUAGUGGAGACACUAUGCGCUGGUUAGCAGGGAUGAUCGAUUCAAGGUCAUACCUAAUGCAAUUUCAUCGCCCUACAAAGCUAAAGCUCAAACGGAAAUGUCA
RS 2 dot ………((((.(((((…..(((((….))))).)))))))))….((((((….))))))(((.(((…((((((((((((…….)))))).)))..)))….))).)))((…..(((….)))…..))……..
RS 3 seq UAAAAGAAUCGGUAGGUGAGACUACCAUAGGGAUACGGGUUGCUACCGCAAAGCAGUGGAGACACUGUGCGCUGGUCAACAGUUCUUGUCGUGAAGGCAAAAACUAAUGCAAUUACAUGGCCCUAUGAUGUUGAAGCUUGAACGAGAUAAAGUUA
RS 3 dot ……….(((((……)))))((((((((….(((((((.(((…((((((….))))))))).))).)))).)))))))).((((..(((……..)))..)))).((((..(((..((((……..))))..)))..))))

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