Detected as a riboswitch by 6 out of 20 classifiers
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5HSAA024530 Similarity: 0.982 Similarity: 0.982 Similarity: 0.980
UTR: 5HSAA024530
Gene: COX18
MFE: -44.995
ENS: 0.830
Length: 102.
Predicted Ligands:
TPP - 10/20
SAM - 6/20
purine - 2/20
 RS: URS0000AD70C0_1631249
MFE: -33.431
Ligand: TPP
Species: Mesorhizobium prunaredense TPP
 RS: URS0000DD377F_1631247
MFE: -35.831
Ligand: TPP
Species: Mesorhizobium delmotii TPP
 RS: URS00003D8A7D_1773
MFE: -42.344
Ligand: TPP
Species: Mycobacterium tuberculosis TPP
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA024530 URS0000AD70C0_1631249 URS0000DD377F_1631247 URS00003D8A7D_1773
Length 102. 101. 101. 101.
Similarity - 0.982 0.982 0.980
Ensemble Norm 0.830 - - -
MFE -44.995 -33.431 -35.831 -42.344
Ligands - TPP TPP TPP
Gene COX18 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 18. 18. 5.001
Length SE - 1. 1. 1.
Lev Distance - 18. 18. 24.
UBS 5. 8. 8. 6.
BS 0. 0. 0. 0.
ILL 0. 2. 2. 1.
ILR 1. 1. 1. 0.
H 4. 4. 4. 4.
BL 0. 1. 1. 1.
BR 0. 2. 2. 1.
UN 0.167 0.149 0.149 0.198

Sequences

Field Description
UTR seq + 25 gcguaucagccuuggcuggccgguguauguccgcuggauugugaggcccgggaucugggcuccgccguggugcagaaATGCTGTGCCGGCTCGGCGGTCGGT
UTR dot + 25 …..(((((….)))))((((((……))))))…….(((((((…)))))))((((((((((((((…..))))))))…))))))…..
RS 1 seq CGCCAUCCACAGGGGUGCUCCGUAUCGCCGGGGCUGAGAGAUGGGCUGCAAGCCCGUAAACCCUAGAGCUGAUCUGGAUAAUACCAGCGGAGCGAGGCGGG
RS 1 dot …(((((….)))))(((((……)))))…….(((((((…)))))))…((((.(..(((..((((……)))))))..).))).)..
RS 2 seq CGCCAUCCACAGGGGUGCUCCGUGUCGUCGGGGCUGAGAGACGGGCUGCAAGCCCGUAAACCCUAGAGCUGAUCUGGAUAAUACCAGCGGAGCGAGGCGGG
RS 2 dot …(((((….)))))(((((……)))))…….(((((((…)))))))…((((.(..(((..((((……)))))))..).))).)..
RS 3 seq GGGUACCCACGCGGGAGCGCACGCCGAGUGCGCUGAGAGGACGGCUCGGGGCCGUCGACCGUACGAACCUGACCGGGUAAUGCCGGCGUAGGGAGUUGCAA
RS 3 dot …..(((….)))(((((((…..)))))))…..(((((((…)))))))..((.((((…….((((……)))))))).))……..

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