Detected as a riboswitch by 14 out of 20 classifiers
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5HSAA034717 Similarity: 0.978 Similarity: 0.978 Similarity: 0.978
UTR: 5HSAA034717
Gene: EIF6_0
MFE: -25.746
ENS: 0.872
Length: 91.
Predicted Ligands:
zmp-ztp - 6/20
guanidine - 5/20
TPP - 5/20
RS: URS00021EDB51_1007676
MFE: -26.551
Ligand: guanidine
Species: Companilactobacillus ginsenosidimutans guanidine-IV riboswitch
RS: URS0000C1D641_12908
MFE: -29.498
Ligand: zmp-ztp
Species: unclassified sequences ZMP/ZTP riboswitch
RS: URS0000C61D36_1469144
MFE: -42.686
Ligand: glycine
Species: Streptomyces thermoautotrophicus Glycine riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA034717 URS00021EDB51_1007676 URS0000C1D641_12908 URS0000C61D36_1469144
Length 91. 91. 92. 93.
Similarity - 0.978 0.978 0.978
Ensemble Norm 0.872 - - -
MFE -25.746 -26.551 -29.498 -42.686
Ligands - guanidine zmp-ztp glycine
Gene EIF6 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 10.008 4.006 6.003
Length SE - 0. 1. 4.
Lev Distance - 26. 27. 23.
UBS 6. 4. 5. 6.
BS 0. 0. 0. 0.
ILL 2. 0. 2. 1.
ILR 0. 0. 1. 2.
H 3. 2. 2. 3.
BL 1. 2. 1. 1.
BR 2. 2. 1. 1.
UN 0.165 0.253 0.087 0.108

Sequences

Field Description
UTR seq + 25 aaaccuuuuuagggaguccaagguacagucgccgcgugcggagcuuguuacugguuacuuggccucATGGCGGTCCGAGCTTCGTTCGAGA
UTR dot + 25 …(((….)))……..(((……))).((.((((((((((..(((………(((….)))))).)))))))))).))…
RS 1 seq UUAUAUACACCGCCGGGUGUCAAAUUUAAAAAGAGUACUUCUAAUAAUUCCGUUAGGCCAAAGUAGGAAUUAUCAGGGGCACUCUAUUUUU
RS 1 dot ……(((((….)))))………..(((((.(((((.((((((((…………..)))))))).))))).)))))……
RS 2 seq AAACGACCAUACGACUGACGGAAGUGGAGCAACCACAUGGAGUGUGGCCGGACGUAAACCGCGUCCUCUUGCCGACCGUCUGGGCACACUGA
RS 2 dot ……((((………….((((…..))))))))((((((.(((((((……(((……)))….))))))).))))))..
RS 3 seq GAAUCCCGAGUGGGAGAGACCCGCCGCGUCAGGCGGGCGCCGAAGGAGCAACCACCCCCGGAAGCUUUCCGGCACAGCUACCGCUCGGCGGAG
RS 3 dot …((((….))))….((((((……))))))((((((.(((((……..((((((…))))))….))).))..))))))…

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