Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA037306 Similarity: 0.992 Similarity: 0.989 Similarity: 0.989
UTR: 5HSAA037306
Gene: EXOSC3
MFE: -18.156
ENS: 0.971
Length: 49.
Predicted Ligands:
unknown - 11/20
SAM - 4/20
preQ_1 - 4/20
 RS: URS0000C3C0C6_1715693
MFE: -14.998
Ligand: SAM
Species: Phaeobacter sp. CECT 7735 SAM/SAH riboswitch
 RS: URS0000E60555_207745
MFE: -14.269
Ligand: unknown
Species: Variovorax sp. WDL1 nhaA-I RNA
 RS: URS0000D6BBBA_12908
MFE: -12.930
Ligand: unknown
Species: unclassified sequences DUF1646 RNA
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA037306 URS0000C3C0C6_1715693 URS0000E60555_207745 URS0000D6BBBA_12908
Length 49. 49. 51. 49.
Similarity - 0.992 0.989 0.989
Ensemble Norm 0.971 - - -
MFE -18.156 -14.998 -14.269 -12.930
Ligands - SAM unknown unknown
Gene EXOSC3 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 1.002 3.009 4.
Length SE - 0. 4. 0.
Lev Distance - 11. 10. 14.
UBS 3. 4. 4. 3.
BS 0. 0. 0. 0.
ILL 0. 0. 0. 1.
ILR 0. 0. 0. 1.
H 2. 2. 2. 2.
BL 1. 1. 2. 0.
BR 1. 1. 0. 0.
UN 0.143 0.102 0.235 0.143

Sequences

Field Description
UTR seq + 25 aaacgguguuugguggagcccgcgATGGCCGAACCTGCGTCTGTCGCGG
UTR dot + 25 …….((((….))))(((((((((.((……)).)))))))))
RS 1 seq CUGUCGUCACAACGGCUUCCUGGCGUGACGAUCAAUACCCAGUGGAGCA
RS 1 dot ….(((….)))(((((((((.(((……..))))))).))))).
RS 2 seq GGGUGUCACACAUGGGGUGGGGCAGGUUUGUGCGAUGGUCGGGCCGCCACG
RS 2 dot ……..(((…..))).(((.((((((.((….)))))))))))…
RS 3 seq GGUUGGGCAGGUAACUGCUUUCAAGUUUUGAGCUUAAGGGUGGAAAGCU
RS 3 dot ….((((((….))))))…((((((..(((….)))..))))))

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