Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA041681 Similarity: 0.986 Similarity: 0.986 Similarity: 0.983
UTR: 5HSAA041681
Gene: FOXB1
MFE: -9.489
ENS: 0.983
Length: 39.
Predicted Ligands:
SAM - 12/20
preQ_1 - 5/20
zmp-ztp - 1/20
 RS: URS00023316D7_471853
MFE: -15.636
Ligand: zmp-ztp
Species: Beutenbergia cavernae DSM 12333 ZMP/ZTP riboswitch
 RS: URS00021EDF1A_12908
MFE: -9.296
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
 RS: URS00021EDBDC_12908
MFE: -10.217
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA041681 URS00023316D7_471853 URS00021EDF1A_12908 URS00021EDBDC_12908
Length 39. 41. 41. 41.
Similarity - 0.986 0.986 0.983
Ensemble Norm 0.983 - - -
MFE -9.489 -15.636 -9.296 -10.217
Ligands - zmp-ztp SAM SAM
Gene FOXB1 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 3.001 5.034 3.053
Length SE - 4. 4. 4.
Lev Distance - 14. 14. 18.
UBS 3. 3. 2. 3.
BS 0. 0. 0. 0.
ILL 0. 1. 1. 1.
ILR 0. 1. 1. 1.
H 2. 2. 1. 2.
BL 1. 0. 0. 0.
BR 0. 0. 0. 0.
UN 0.231 0.195 0.415 0.

Sequences

Field Description
UTR seq + 25 aaggcgauugucauATGCCTCGGCCCGGCCGCAACACGT
UTR dot + 25 .((((.((……))))))((((…))))……..
RS 1 seq GUCGCGACUGGCGCCGAGGUGGAUCACCACCGGGGAGCGAC
RS 1 dot ..(((…..)))((..(((((….)))))..))……
RS 2 seq CACGCAACGGCUUCCUGACGCGUGAGAUUAAUAUUGGAGCA
RS 2 dot (((((..(((….)))..)))))……………..
RS 3 seq CCUACAACGGCUUCCUGAAGUAGGUGUUUUUUUUUGGAGCA
RS 3 dot (((((..(((….)))..)))))((((((…..))))))

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