Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA047795 Similarity: 0.983 Similarity: 0.981 Similarity: 0.981
UTR: 5HSAA047795
Gene: HAGHL
MFE: -28.525
ENS: 0.984
Length: 75.
Predicted Ligands:
fluoride - 6/20
glycine - 5/20
cobalamin - 3/20
 RS: URS0000C00247_401053
MFE: -19.304
Ligand: fluoride
Species: Terriglobus saanensis SP1PR4 Fluoride riboswitch
 RS: URS0000DAFD26_1895740
MFE: -33.193
Ligand: fluoride
Species: Cellulomonas sp. 73-92 Fluoride riboswitch
 RS: URS0000D6795D_12908
MFE: -25.450
Ligand: Ni/Co
Species: unclassified sequences NiCo riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA047795 URS0000C00247_401053 URS0000DAFD26_1895740 URS0000D6795D_12908
Length 75. 74. 75. 76.
Similarity - 0.983 0.981 0.981
Ensemble Norm 0.984 - - -
MFE -28.525 -19.304 -33.193 -25.450
Ligands - fluoride fluoride Ni/Co
Gene HAGHL - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 2. 19. 14.001
Length SE - 1. 0. 1.
Lev Distance - 21. 17. 18.
UBS 8. 9. 5. 6.
BS 0. 0. 0. 0.
ILL 1. 1. 0. 1.
ILR 1. 2. 0. 0.
H 2. 2. 2. 2.
BL 5. 5. 3. 2.
BR 4. 4. 2. 4.
UN 0.107 0.095 0.120 0.132

Sequences

Field Description
UTR seq + 25 gguccucagcacagccgugccgcaggcaccgguggccgagcuccgugaccATGAAGGTCAAGGTCATCCCCGTGC
UTR dot + 25 ((..(((.((.((.(.(((((…))))).).)))).)))..))((((((.(((…))).))))))……..
RS 1 seq AACAACCUGGGCGAUGGGGUUCCGCCACUAACCGCACGCGCUGUAUGCGCGGAGCUGAUGACUCCUACGAGACA
RS 1 dot ..((..(.(.(((.((.((((……..)))).))))).).)..))((.(((((….).))))..))…..
RS 2 seq GUCGCCGUCGGCGAUGGAUCCCGCCCGCGUCGAUGACGACGGAACCGCCGGCCGGCUGAUGGUUCCUGCUCCCAG
RS 2 dot ((((.((((((((.(((…….))))))))))).))))(((((((.(((….))).)))))))………
RS 3 seq GUUUCAUCCAUUGAUCAGGCCCAGGGGAGCCGGGUCGCGGAUGCGGCAGCAGAAAUUUGUGAUCUGCGGGACAGGC
RS 3 dot (((.(((((..(((((.(((((…)).))).))))).))))).))).(((((………)))))………

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