Detected as a riboswitch by 2 out of 20 classifiers
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5HSAA050773 Similarity: 0.981 Similarity: 0.980 Similarity: 0.980
UTR: 5HSAA050773
Gene: HPSE2
MFE: -17.330
ENS: 0.804
Length: 85.
Predicted Ligands:
GMP - 12/20
zmp-ztp - 3/20
cyclic-di-GMP - 2/20
 RS: URS0000D6B2FA_12908
MFE: -30.108
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
 RS: URS0000D69732_12908
MFE: -35.923
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
 RS: URS0000D68F64_12908
MFE: -27.918
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA050773 URS0000D6B2FA_12908 URS0000D69732_12908 URS0000D68F64_12908
Length 85. 85. 85. 85.
Similarity - 0.981 0.980 0.980
Ensemble Norm 0.804 - - -
MFE -17.330 -30.108 -35.923 -27.918
Ligands - GMP GMP GMP
Gene HPSE2 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 1.003 3. 1.
Length SE - 0. 0. 0.
Lev Distance - 26. 26. 27.
UBS 6. 6. 5. 6.
BS 0. 0. 0. 0.
ILL 1. 1. 1. 1.
ILR 0. 0. 1. 1.
H 3. 3. 3. 3.
BL 0. 0. 0. 0.
BR 2. 3. 1. 2.
UN 0.153 0.094 0.153 0.141

Sequences

Field Description
UTR seq + 25 aaggacaauuagucacuagcgagacccaguaggaagagagguuuaaaucagagggauugaATGAGGGTGCTTTGTGCCTTCCCTG
UTR dot + 25 .(((((…..))).))….((((((……….).)))))…….(((((……..((((((…))))))))))).
RS 1 seq ACGACGGCGGGAGGCGCCGACACGUGGUCCAUUCCCUUGUCGCCGGGAUCACGCCGAGCCAAUGGCGAGACCGACCCGCUCAGGC
RS 1 dot ….(((((…..)))))….(((((((……………)))))))(((((((….((((….)).)).)))).)))
RS 2 seq ACCGCAGCGGGAGGCUGUGACGCGCGGCCCACACCCCGGCCGCCGGGACCGCGCCGAGCCACUGGCGAGACCGACCCGUAUAUGG
RS 2 dot ..((((((…..))))))….((((((……..))))))((((..(((((((……)))))….)).))))…….
RS 3 seq CCAGACACGGGGAGCUCUGACACGCGGCCCACACUCUGGCCGCCGGGACCGCGCCGAGCCACUGGCGAGACCGACCCGCGAUGAG
RS 3 dot .(((((…….).))))….((((((……..))))))((((..(((((((……)))))….)).))))…….

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