Detected as a riboswitch by 2 out of 20 classifiers
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5HSAA058632 Similarity: 0.990 Similarity: 0.989 Similarity: 0.987
UTR: 5HSAA058632
Gene: LEO1
MFE: -5.441
ENS: 0.722
Length: 41.
Predicted Ligands:
SAM - 14/20
preQ_1 - 4/20
guanidine - 1/20
 RS: URS00021EDBDC_12908
MFE: -10.217
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
 RS: URS00021EDED0_12908
MFE: -11.950
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
 RS: URS00021EE04B_12908
MFE: -9.549
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA058632 URS00021EDBDC_12908 URS00021EDED0_12908 URS00021EE04B_12908
Length 41. 41. 42. 43.
Similarity - 0.990 0.989 0.987
Ensemble Norm 0.722 - - -
MFE -5.441 -10.217 -11.950 -9.549
Ligands - SAM SAM SAM
Gene LEO1 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 0.021 0. 0.010
Length SE - 0. 1. 4.
Lev Distance - 14. 14. 14.
UBS 3. 3. 3. 3.
BS 0. 0. 0. 0.
ILL 1. 1. 1. 1.
ILR 1. 1. 1. 1.
H 2. 2. 2. 2.
BL 0. 0. 0. 0.
BR 0. 0. 0. 0.
UN 0.146 0. 0.143 0.047

Sequences

Field Description
UTR seq + 25 gcggacgugagcgauaATGGCGGATATGGAGGATCTCTTCG
UTR dot + 25 …..((((..((…….))..))))((((….)))).
RS 1 seq CCUACAACGGCUUCCUGAAGUAGGUGUUUUUUUUUGGAGCA
RS 1 dot (((((..(((….)))..)))))((((((…..))))))
RS 2 seq GCCACAACGGCUUCCUGGCGUGGCAAUUUUUCUAAUGGAGCG
RS 2 dot (((((..(((….)))..)))))….((((….))))..
RS 3 seq UGUCACAACGGCUUCCUGGCGUGGCACUUUUUAUAAUGGAGCG
RS 3 dot ((((((..(((….)))..))))))((((…….))))..

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