Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA062043 Similarity: 0.984 Similarity: 0.981 Similarity: 0.981
UTR: 5HSAA062043
Gene: MAN1A1
MFE: -23.418
ENS: 0.987
Length: 91.
Predicted Ligands:
TPP - 6/20
GMP - 4/20
SAM - 3/20
 RS: URS0000D67F2B_12908
MFE: -38.683
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
 RS: URS0000D674D4_12908
MFE: -35.575
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
 RS: URS0000D6AEA8_12908
MFE: -22.999
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA062043 URS0000D67F2B_12908 URS0000D674D4_12908 URS0000D6AEA8_12908
Length 91. 91. 92. 92.
Similarity - 0.984 0.981 0.981
Ensemble Norm 0.987 - - -
MFE -23.418 -38.683 -35.575 -22.999
Ligands - GMP GMP GMP
Gene MAN1A1 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 3.002 3.002 0.
Length SE - 0. 1. 1.
Lev Distance - 21. 23. 25.
UBS 5. 5. 5. 5.
BS 0. 0. 0. 0.
ILL 1. 1. 1. 1.
ILR 2. 1. 2. 2.
H 2. 3. 3. 2.
BL 1. 0. 0. 1.
BR 1. 1. 0. 1.
UN 0.209 0.165 0.163 0.196

Sequences

Field Description
UTR seq + 25 ccgaccggccguguuuuucagggagaaacggcaagccuuugaaacucugaagacugcaacaaugcaATGCCCGTGGGGGGCCTGTTGCCGC
UTR dot + 25 ……….(((.(((((((((……((….))…….))))))))).)))……(((((((((…..))))..)))))…
RS 1 seq CACGAGGGUAGAGGCCUUGAUACCCGCCCCGCAACACCCCGAGGCACCUACGGGGCGGGAGGAGCCAGUGGUGCGACCGGCUACCGCUACG
RS 1 dot ..(((((…….)))))…(((((((((…..((….))……)))))))))…….((((((((…..)).))))))…
RS 2 seq GGCCGGGCGAGAGGCGCUCGAACCGCGGCCGGUAUGCCGGUCACCGAUCAAAUGGCCGCGGCUAGCCAAUGGUGAGACCGACUCGAACCACU
RS 2 dot …((((((…..))))))..(((((((((……(((…)))……)))))))))……..(((((((…..)))..))))..
RS 3 seq UCCACAGGUAGAGGCUAAGAAGCUCGUCCCGAAAGAAACACGGGCGCCCUAGGGAACGAGCGGAGCCAUUGGCGCGACCGGCUACCCACGAG
RS 3 dot …………((((…..(((((((((…………………)))).)))))..))))..(((.((…..))…)))….

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