Detected as a riboswitch by 15 out of 20 classifiers
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5HSAA062271 Similarity: 0.981 Similarity: 0.981 Similarity: 0.979
UTR: 5HSAA062271
Gene: MAP2K1
MFE: -23.836
ENS: 0.909
Length: 96.
Predicted Ligands:
TPP - 13/20
zmp-ztp - 2/20
cobalamin - 2/20
RS: URS0000C0BDD2_12908
MFE: -33.694
Ligand: zmp-ztp
Species: unclassified sequences ZMP/ZTP riboswitch
RS: URS0000C16F93_12908
MFE: -33.694
Ligand: zmp-ztp
Species: unclassified sequences ZMP/ZTP riboswitch
RS: URS0000C1F70A_69370
MFE: -29.365
Ligand: glycine
Species: Microbacterium trichothecenolyticum Glycine riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA062271 URS0000C0BDD2_12908 URS0000C16F93_12908 URS0000C1F70A_69370
Length 96. 96. 96. 97.
Similarity - 0.981 0.981 0.979
Ensemble Norm 0.909 - - -
MFE -23.836 -33.694 -33.694 -29.365
Ligands - zmp-ztp zmp-ztp glycine
Gene MAP2K1 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 3.002 3.002 7.003
Length SE - 0. 0. 1.
Lev Distance - 25. 25. 25.
UBS 8. 8. 8. 9.
BS 0. 0. 0. 0.
ILL 2. 2. 2. 1.
ILR 2. 1. 1. 2.
H 3. 3. 3. 3.
BL 1. 2. 2. 3.
BR 2. 1. 1. 3.
UN 0.146 0.104 0.104 0.093

Sequences

Field Description
UTR seq + 25 aaagccugggaugugcagagaagccagcaaguaguugagugugacgggugcaucgguucgggucgaaggaaATGCCCAAGAAGAAGCCGACGCCCA
UTR dot + 25 …..((((..(.(….).)..))))(((….)))……..(((((..(((((((((((……….))))…..))).))))))))).
RS 1 seq UAGGCGCCGUGCAACUGACGGAAAGCCCAUUUGGGCAGGCAGGCUAAACUGCCGGGGAACGCGGCGUAUAAAAAGCCGACCGUCUGGGCAGCCUCU
RS 1 dot ……((((…….))))…((((….)))).((.((((…..((((.((..(((((((………))))..))))).))))))))))
RS 2 seq UAGGCGCCGUGUAACUGACGGAAAGCCCAUUUGGGCAGGCAGGCUAAACUGCCGGGGAACGCGGCGUAUAAAAAGCCGACCGUCUGGGCAGCCUCU
RS 2 dot ……((((…….))))…((((….)))).((.((((…..((((.((..(((((((………))))..))))).))))))))))
RS 3 seq AUCACCCGGGCGGGAGAGCCUCGGCAGCGUGAUCGCCGAGCACCGAAGGAGCAAGCCUCCCCGCCAAUCUCUCAGGUACGCGUACCGUUCGGGCAGG
RS 3 dot …..((((((……))).)))(.(((….))).).((.(((((((.((..((((……………))))..))…)).)))))))…

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