Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA067411 Similarity: 0.965 Similarity: 0.963 Similarity: 0.961
UTR: 5HSAA067411
Gene: MRPL22_1
MFE: -39.225
ENS: 0.962
Length: 159.
Predicted Ligands:
cobalamin - 6/20
FMN - 5/20
glucosamine - 4/20
 RS: URS0002327137_317936
MFE: -35.538
Ligand: cobalamin
Species: Nostoc sp. PCC 7107 Cobalamin riboswitch
 RS: URS0002330387_1170562
MFE: -33.501
Ligand: cobalamin
Species: Calothrix sp. PCC 6303 Cobalamin riboswitch
 RS: URS0000AB99DE_290633
MFE: -59.703
Ligand: FMN
Species: Gluconobacter oxydans 621H FMN riboswitch (RFN element)
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA067411 URS0002327137_317936 URS0002330387_1170562 URS0000AB99DE_290633
Length 159. 159. 158. 158.
Similarity - 0.965 0.963 0.961
Ensemble Norm 0.962 - - -
MFE -39.225 -35.538 -33.501 -59.703
Ligands - cobalamin cobalamin FMN
Gene MRPL22 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 4.011 5.003 7.
Length SE - 0. 1. 1.
Lev Distance - 45. 46. 48.
UBS 9. 8. 9. 11.
BS 0. 0. 0. 0.
ILL 2. 1. 1. 2.
ILR 1. 2. 2. 2.
H 3. 3. 4. 3.
BL 2. 3. 3. 3.
BR 3. 3. 2. 4.
UN 0.170 0.277 0.228 0.165

Sequences

Field Description
UTR seq + 25 gagauggaaucugaguugacggcuuguguugauguugcaggugcguuauggauacauaaccugaggagccgggggaagcuggccuuggggaaaucuaccacugucgaagacaaauaaaauauagcaaagacaagATGTGGTATTTGGCAAAATTGATAC
UTR dot + 25 …(((..(((((…((((((((((((…….))))))).)))))))))).)))..(((.(((.(((((……)))))))).)))…..((((((((((…………………..))))….))))))……………..
RS 1 seq AUAAUAAACAGAAUAUUCGGUUUUGGUGGAGAUCAGCCACCAAAGGUAACGGGGAAAGUUCGGUGGAAAUCCGGCACUGUCCCGCAACUGUGAAGGAAAGACAAAAAACUGAAAAUUAACUUUCCAAGUCAGGAUGCCCGCCGAAGUAUACUAAUAAGU
RS 1 dot ………………(.(((((((((…….))))))))).)….((((.(((((((…….)))).))).))))(((.(((….((((((……………….))))))….)))..)))………………….
RS 2 seq AGCAUUCACCUUAAUCUCGGUUCUAGUGAGUAUCAUCCACUAGAGGUAACGGGGAAAGUCCGGUGUAAGUCCGGCGCUGUCCCGCAGCUGUAAUCAAGGAAAAAAAGAAAAAUAUUAACCUUGUCAGUCAGAAUGCCCGCCGAUAAGUCAAAACAACC
RS 2 dot ……..((……..))((((((((.(……)))))))))……((((.(((((((…….)))).))).))))(((.(((….(((((……………….)))))…..)))..)))………………….
RS 3 seq AGACGUUCUCAGGGCGGGGUGAAAUUCUCCACCGGCGGUAUUGGCGGAUUUCUCCGCCUCAGCCCGCGAGCGCCUUCCGGAUUUCGGUUCGGAAGGGACAAGCAGAUCCGGUGAGACUCCGGAGCCGACGGUUAGAGUCCGGAUGGAAGAGAACGCAG
RS 3 dot …(((((.(.((((((((((((((((.(((((…)))…)).)))))))…))))).))))).)))))((((((((((….))))))))))………((((((….((((…((((…)))).))))))))))…………..

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