Detected as a riboswitch by 15 out of 20 classifiers
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5HSAA068260 Similarity: 0.985 Similarity: 0.985 Similarity: 0.984
UTR: 5HSAA068260
Gene: MTBP
MFE: -16.559
ENS: 0.921
Length: 70.
Predicted Ligands:
fluoride - 8/20
cobalamin - 4/20
aminoglycoside - 3/20
RS: URS0002314F36_235986
MFE: -18.850
Ligand: cobalamin
Species: Streptomyces glauciniger Cobalamin riboswitch
RS: URS0000C06E39_1588750
MFE: -8.612
Ligand: fluoride
Species: Clostridiales bacterium KA00134 Fluoride riboswitch
RS: URS0000E5FA5C_1484158
MFE: -12.092
Ligand: aminoglycoside
Species: Pantoea sp. PSNIH1 putative aminoglycoside riboswitch / attI site
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA068260 URS0002314F36_235986 URS0000C06E39_1588750 URS0000E5FA5C_1484158
Length 70. 68. 70. 71.
Similarity - 0.985 0.985 0.984
Ensemble Norm 0.921 - - -
MFE -16.559 -18.850 -8.612 -12.092
Ligands - cobalamin fluoride aminoglycoside
Gene MTBP - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 7. 8. 3.038
Length SE - 4. 0. 1.
Lev Distance - 13. 18. 20.
UBS 4. 4. 5. 3.
BS 0. 0. 0. 0.
ILL 3. 1. 2. 2.
ILR 3. 2. 2. 2.
H 1. 1. 1. 1.
BL 0. 1. 1. 0.
BR 0. 1. 2. 0.
UN 0.171 0.191 0.171 0.366

Sequences

Field Description
UTR seq + 25 gauguggaagccgagaccuaaaguuggggggugaucucugaggagATGGATCGGTACCTGCTGCTGGTGA
UTR dot + 25 …((((..(((((..(……(((((((….)))))))……)..)))))..))))………
RS 1 seq GGAAGUCCGGUGCAAAUCCGGCACGGUCGCGCCACUGUAAGCCCAGCCCAGCGCCAGGCGAGUCAGAC
RS 1 dot ….(((.(((((……((((((((……)))))..)))…….))))).)))………
RS 2 seq AUGUUUAGAGGAAAUGAGGUACUUCCUUGGGAAACCUAAAUGCAAAUAUGCUGAUGACUUCUACUUUUGU
RS 2 dot …..((((((..((.(((((…..(((((…)))))…….))).)).))..))))))…….
RS 3 seq GGAGCAGCAACGAUGUUACGCAGCAGGGCAGUCGCCCUAAAACAAAGUUAGGCAUCACAAAGUACAGCAUC
RS 3 dot ………..((((((..((…(((((….)))))……..))..))))))……………

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