Detected as a riboswitch by 15 out of 20 classifiers
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5HSAA069230-1 Similarity: 0.974 Similarity: 0.974 Similarity: 0.974
UTR: 5HSAA069230-1
Gene: MYL6
MFE: -26.646
ENS: 0.897
Length: 111.
Predicted Ligands:
methionine - 8/20
TPP - 5/20
SAM - 4/20
 RS: URS0000D89830_134962
MFE: -50.830
Ligand: methionine
Species: Nocardia soli S-adenosyl methionine (SAM) riboswitch,
 RS: URS0000AB355D_247156
MFE: -49.580
Ligand: methionine
Species: Nocardia farcinica IFM 10152 S-adenosyl methionine (SAM) riboswitch,
 RS: URS0000C4AAB8_1794906
MFE: -39.024
Ligand: TPP
Species: Marinobacter sp. T13-3 TPP riboswitch (THI element)
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA069230-1 URS0000D89830_134962 URS0000AB355D_247156 URS0000C4AAB8_1794906
Length 111. 111. 111. 112.
Similarity - 0.974 0.974 0.974
Ensemble Norm 0.897 - - -
MFE -26.646 -50.830 -49.580 -39.024
Ligands - methionine methionine TPP
Gene MYL6 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 7. 7. 2.004
Length SE - 0. 0. 1.
Lev Distance - 32. 32. 33.
UBS 9. 9. 9. 9.
BS 0. 0. 0. 0.
ILL 3. 4. 4. 2.
ILR 4. 2. 2. 4.
H 2. 2. 2. 2.
BL 3. 2. 2. 3.
BR 2. 3. 3. 1.
UN 0.135 0.117 0.117 0.196

Sequences

Field Description
UTR seq + 25 gucaucgggacguacuaagacuaggguugggccgagagucggagccauuacugcaggaaaaggucccggagagcugagcagucaagATGTGTGACTTCACCGAAGACCAGA
UTR dot + 25 .((.(((((((.(…….((..((((((.((((…))))..)))..)))..))….).))))))).))..(((..(((((…….))))))))…………
RS 1 seq GGUCAUGAGUACCAGCGUCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCAGCUGCGGUGGGGUGCUCCGGGUGAUGACCGGGCCCUCGAAGGUCGAGGGCAAGCGCGCAUU
RS 1 dot ((((((…((((..((…((((((.(((.(((((..((…))..)))))…))).))).))).))))))))))))..((((((((…))))))))………..
RS 2 seq GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAGCUGCGGUGGGGUGCUCCGGGUGAUGACCGGGCUCCCGAAGGUCGGGGGCAAGCGCGCUCG
RS 2 dot ((((((…((((..((…((((((.(((.(((((..((…))..)))))…))).))).))).))))))))))))..((((((((…))))))))………..
RS 3 seq CGCGUCUUGACGGGGUGCUGGCGGCCAGAAAUGGCGGCCGGCUGAGAUUGCAACGCAGAACCCGCAACCUGAUCCGGAUAAUACCGGCGUAGGGAUUAAGACCAGAUGAACA
RS 3 dot .(((((.((.((..((((((((.((((….)))).))))))…….))..))))))…)))..((((..((((……))))..))))……………….

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