Detected as a riboswitch by 20 out of 20 classifiers
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5HSAA083307 Similarity: 0.980 Similarity: 0.979 Similarity: 0.979
UTR: 5HSAA083307
Gene: PPIA
MFE: -31.876
ENS: 0.982
Length: 108.
Predicted Ligands:
TPP - 13/20
guanidine - 4/20
GMP - 1/20
 RS: URS0000D693E3_12908
MFE: -40.406
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GAG riboswitch
 RS: URS0000AB9D17_350058
MFE: -59.944
Ligand: guanidine
Species: Mycobacterium vanbaalenii PYR-1 Guanidine-I riboswitch
 RS: URS0000C4844F_1604022
MFE: -29.237
Ligand: TPP
Species: Pseudomonas sp. FeS53a TPP riboswitch (THI element)
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA083307 URS0000D693E3_12908 URS0000AB9D17_350058 URS0000C4844F_1604022
Length 108. 107. 110. 107.
Similarity - 0.980 0.979 0.979
Ensemble Norm 0.982 - - -
MFE -31.876 -40.406 -59.944 -29.237
Ligands - GMP guanidine TPP
Gene PPIA - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 0. 2. 1.006
Length SE - 1. 4. 1.
Lev Distance - 26. 22. 27.
UBS 10. 10. 10. 10.
BS 0. 0. 0. 0.
ILL 2. 2. 2. 2.
ILR 2. 2. 1. 2.
H 2. 2. 2. 1.
BL 5. 5. 5. 5.
BR 5. 5. 4. 5.
UN 0.083 0.084 0.073 0.159

Sequences

Field Description
UTR seq + 25 gaacgugguauaaaaggggcgggaggccaggcucgugccguuuugcagacgccaccgccgaggaaaaccguguacuauuagccATGTGTCAGGGTGGTGACTTCACAC
UTR dot + 25 ..(((((((.(((.(((.((((….((.(((..(((.(((((…))))).))).)))..))….)))).).)).))))))))))((((……))))…….
RS 1 seq GCUCCUACGGAACGUGAUGAUCCGGAUGGUCCGCCUCUCCCGCAGAGGCGAACUCGGCCGCCUAAUGGCCAUCCGGGGAGCGAGUGGCGAGACCGGUCCGUUCUGAC
RS 1 dot ((((((.((((..((.((….(((.((((.(((((((…..))))))).)).)).)))….)).))..))))))))))((.(((…..))).))………
RS 2 seq GUGGGGCGCGCCUAGGGUUCCGCCGGCAGGCAGCCGGGUCUGGUCCGAGAGGCGCAGGCGGCCGGCACCGGAGCCCGGCCGUUCCACGGCGGGACAAAAGCCCGGGAGAC
RS 2 dot ((((((((.(((..((((((((…((.(((.((((.((((……..)))).).))).))).))..)))))))))))))))))))..((((.(….)))))……
RS 3 seq GAGUUCUUGUCGGGGUGCCUCGAAUCGGAGGCUGAGAUCGGAAAGUUCCGGAUCCCGUUGAACCUGAUCAGGUUAAGGCCUGCGUAGGGAACAAGAUGUGCCUCUCC
RS 3 dot ..((((((..((.((.((((..((((.(((((.(.(((((((….)))).)))).)))……..)).)))).)))))).))..))))))……………

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