Detected as a riboswitch by 12 out of 20 classifiers
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5HSAA084599 Similarity: 0.988 Similarity: 0.988 Similarity: 0.988
UTR: 5HSAA084599
Gene: PRKAR2B
MFE: -16.381
ENS: 0.869
Length: 51.
Predicted Ligands:
glutamine - 12/20
SAM - 8/20

 RS: URS00021EDD96_12908
MFE: -16.813
Ligand: SAM
Species: unclassified sequences SAM-SAH-Weickhmann-2018 RNA
 RS: URS0000C56388_12908
MFE: -11.443
Ligand: glutamine
Species: unclassified sequences Glutamine riboswitch
 RS: URS0000C668B9_12908
MFE: -8.554
Ligand: glutamine
Species: unclassified sequences Glutamine riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA084599 URS00021EDD96_12908 URS0000C56388_12908 URS0000C668B9_12908
Length 51. 51. 51. 52.
Similarity - 0.988 0.988 0.988
Ensemble Norm 0.869 - - -
MFE -16.381 -16.813 -11.443 -8.554
Ligands - SAM glutamine glutamine
Gene PRKAR2B - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 16. 9. 9.001
Length SE - 0. 0. 1.
Lev Distance - 10. 13. 12.
UBS 6. 4. 4. 4.
BS 0. 0. 0. 0.
ILL 0. 1. 0. 0.
ILR 0. 1. 0. 0.
H 2. 2. 2. 2.
BL 1. 0. 2. 2.
BR 4. 1. 2. 2.
UN 0.176 0.176 0.157 0.212

Sequences

Field Description
UTR seq + 25 agccgccgccaccacccggaggcaggATGAGCATCGAGATCCCGGCGGGAC
UTR dot + 25 .(((((((((.((….)).))).)).)).))…….((((…)))).
RS 1 seq CCGCCCACAACGGCUUCCUGGCGUGGCGCGGCAAAAACCUCAAACGGAGCA
RS 1 dot ((((((((..(((….)))..)))).))))…….(((…..)))..
RS 2 seq UACGUUCAUCCUACAAAAGGACGGAAGUAGCACUAUGCGAAGGAACGCACU
RS 2 dot (((.(((.((((…..)))).))).)))……((((……))))..
RS 3 seq AACGUUCAUCUUUUUUUAAAAGACGGAAGUAGCGAAAGCGAAGGAACGCACC
RS 3 dot .((.(((.((((((…)))))).))).))…….(((……)))…

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