Detected as a riboswitch by 18 out of 20 classifiers
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5HSAA088027 Similarity: 0.984 Similarity: 0.984 Similarity: 0.983
UTR: 5HSAA088027
Gene: RAD17
MFE: -10.380
ENS: 0.941
Length: 87.
Predicted Ligands:
zmp-ztp - 18/20
cyclic-di-GMP - 2/20

RS: URS0000DA3CDD_235986
MFE: -41.133
Ligand: zmp-ztp
Species: Streptomyces glauciniger ZMP/ZTP riboswitch
RS: URS0000C1C31F_1725411
MFE: -41.775
Ligand: zmp-ztp
Species: Streptomyces sp. CdTB01 ZMP/ZTP riboswitch
RS: URS0000C4C360_68231
MFE: -45.736
Ligand: zmp-ztp
Species: Streptomyces longwoodensis ZMP/ZTP riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA088027 URS0000DA3CDD_235986 URS0000C1C31F_1725411 URS0000C4C360_68231
Length 87. 87. 88. 88.
Similarity - 0.984 0.984 0.983
Ensemble Norm 0.941 - - -
MFE -10.380 -41.133 -41.775 -45.736
Ligands - zmp-ztp zmp-ztp zmp-ztp
Gene RAD17 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 0.001 3.005 1.001
Length SE - 0. 1. 1.
Lev Distance - 21. 19. 21.
UBS 8. 8. 7. 8.
BS 0. 0. 0. 0.
ILL 0. 0. 0. 1.
ILR 1. 1. 0. 1.
H 3. 3. 3. 3.
BL 3. 3. 3. 3.
BR 3. 3. 4. 3.
UN 0.057 0.034 0.125 0.023

Sequences

Field Description
UTR seq + 25 gugaauuauaguuuaauguacugcaaguccuaaacuacggaugggaacuauuacaguuuauaATGTTTAATACTGAATCAAGCTTCC
UTR dot + 25 (((.((((…..)))).)))…..((((……..))))((((.(((((.(((((((…….))).)))))))..)).))))
RS 1 seq GCCACGGGUCGUGACUGGCGCGCUGGGAUGGGAUUGACCAUCGGGGAGCGGCCCGUGAACUGUGUGCCGUGCGCCUGGGCCGUCCCG
RS 1 dot .(((((.((((….)))).)).)))(((((……))))).((((.(((((((((.((……..)).)))..)))))))))).
RS 2 seq GUGACGGGCCGUGACUGGCGCGCUGGGAUGGGACCGACCAUCGGGGAGCGGCCCGAGCGACUGAGUGCCGUGCGCCUGGGCCGUACCG
RS 2 dot ….((.((((….)))).))….(((((……)))))..((.((((((((.(((((……..)).))).)))))))).)).
RS 3 seq GCCGUGGGCCGUGACUGGCGCGCUGGGAUGGGACCGACCAUCGGGGAGCGGCCCGUUCGACACAGUGCCGUGCGCCUGGGCCGUACCC
RS 3 dot .(((((.((((….)))).))).))(((((……))))).(((.((((((((..((.(((……)))))..)))))))).)))

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