Detected as a riboswitch by 18 out of 20 classifiers
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5HSAA089343 Similarity: 0.985 Similarity: 0.984 Similarity: 0.984
UTR: 5HSAA089343
Gene: RBM26
MFE: -5.801
ENS: 0.918
Length: 39.
Predicted Ligands:
SAM - 11/20
preQ_1 - 6/20
guanidine - 1/20
 RS: URS0000CBFF2B_2021
MFE: -13.547
Ligand: guanidine
Species: RNA (41-MER) from Thermobifida fusca (PDB 5NY8, chain B)
 RS: URS0000BE9632_1514904
MFE: -10.995
Ligand: SAM
Species: Ahrensia marina SAM riboswitch (alpha-proteobacteria)
 RS: URS0000BE9AC2_1514904
MFE: -10.827
Ligand: SAM
Species: Ahrensia marina SAM riboswitch (alpha-proteobacteria)
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA089343 URS0000CBFF2B_2021 URS0000BE9632_1514904 URS0000BE9AC2_1514904
Length 39. 41. 41. 41.
Similarity - 0.985 0.984 0.984
Ensemble Norm 0.918 - - -
MFE -5.801 -13.547 -10.995 -10.827
Ligands - guanidine SAM SAM
Gene RBM26 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 6.095 4.008 4.008
Length SE - 4. 4. 4.
Lev Distance - 14. 16. 16.
UBS 2. 3. 2. 2.
BS 0. 0. 0. 0.
ILL 0. 1. 1. 1.
ILR 0. 1. 1. 1.
H 1. 2. 1. 1.
BL 1. 0. 0. 0.
BR 1. 0. 0. 0.
UN 0.333 0.024 0.244 0.244

Sequences

Field Description
UTR seq + 25 uagggccgcuguggATGGTTTCTAAAATGATCATTGAAA
UTR dot + 25 ………..(.(((((((……..))))))).)..
RS 1 seq CCGGACGAGGUGCGCCGUACCCGGUCAGGACAAGACGGCGC
RS 1 dot ((……)).(((((((..((…..))…..)))))))
RS 2 seq AAUAGAUUUCGUGGUGAUUUGGCCGGUCGGCUUGCAGCCAC
RS 2 dot ……….(((((…..((((….))))….)))))
RS 3 seq GUUAUUCAUUGUGGUGAUUUGGCCGGUCGGCUUGCAGCCAC
RS 3 dot ……….(((((…..((((….))))….)))))

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