Detected as a riboswitch by 19 out of 20 classifiers
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5HSAA093770 Similarity: 0.988 Similarity: 0.985 Similarity: 0.983
UTR: 5HSAA093770
Gene: RUVBL2_0
MFE: -7.384
ENS: 0.957
Length: 39.
Predicted Ligands:
SAM - 15/20
zmp-ztp - 2/20
fluoride - 1/20
 RS: URS0000D92E6B_1802287
MFE: -9.182
Ligand: fluoride
Species: Syntrophobacterales bacterium GWC2_56_13 Fluoride riboswitch
 RS: URS0000D87AB1_1686310
MFE: -13.459
Ligand: SAM
Species: Bartonella apis SAM riboswitch (alpha-proteobacteria)
 RS: URS00023316D7_471853
MFE: -15.636
Ligand: zmp-ztp
Species: Beutenbergia cavernae DSM 12333 ZMP/ZTP riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA093770 URS0000D92E6B_1802287 URS0000D87AB1_1686310 URS00023316D7_471853
Length 39. 38. 36. 41.
Similarity - 0.988 0.985 0.983
Ensemble Norm 0.957 - - -
MFE -7.384 -9.182 -13.459 -15.636
Ligands - fluoride SAM zmp-ztp
Gene RUVBL2 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 7.001 8. 6.014
Length SE - 1. 9. 4.
Lev Distance - 13. 9. 17.
UBS 4. 3. 2. 3.
BS 0. 0. 0. 0.
ILL 1. 0. 1. 1.
ILR 1. 1. 1. 1.
H 1. 1. 1. 2.
BL 2. 0. 0. 0.
BR 0. 1. 0. 0.
UN 0.077 0.053 0.056 0.195

Sequences

Field Description
UTR seq + 25 aguuggugagcaucATGGCAACCGTTACAGCCACAACCA
UTR dot + 25 .(((.(((.((…((((…))))….))))))))..
RS 1 seq GGGGUUCACCGCAACCGCCGCUCGGCUGAUAACUCCUA
RS 1 dot (((((((((((………..))).)))..)))))..
RS 2 seq CGUGGUGAUUUGGGCCGGCCGGCUUGCAGCCACGCU
RS 2 dot ((((((…..(((((….)))))…))))))..
RS 3 seq GUCGCGACUGGCGCCGAGGUGGAUCACCACCGGGGAGCGAC
RS 3 dot ..(((…..)))((..(((((….)))))..))……

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