Detected as a riboswitch by 19 out of 20 classifiers
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5HSAA121739 Similarity: 0.983 Similarity: 0.983 Similarity: 0.983
UTR: 5HSAA121739
Gene: ZFYVE19
MFE: -22.522
ENS: 0.942
Length: 80.
Predicted Ligands:
GMP - 5/20
cyclic-di-GMP - 4/20
SAM - 4/20
 RS: URS0000D6AA3C_12908
MFE: -26.932
Ligand: cyclic-di-GMP
Species: unclassified sequences Cyclic di-GMP-II riboswitch
 RS: URS0000D6B222_12908
MFE: -29.523
Ligand: GMP
Species: unclassified sequences c-di-GMP-II-GCG riboswitch
 RS: URS0000D9683D_1797358
MFE: -27.276
Ligand: cyclic-di-GMP
Species: Bacteroidetes bacterium RBG_13_46_8 Cyclic di-GMP-II riboswitch
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA121739 URS0000D6AA3C_12908 URS0000D6B222_12908 URS0000D9683D_1797358
Length 80. 81. 82. 80.
Similarity - 0.983 0.983 0.983
Ensemble Norm 0.942 - - -
MFE -22.522 -26.932 -29.523 -27.276
Ligands - cyclic-di-GMP GMP cyclic-di-GMP
Gene ZFYVE19 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 3.007 3.009 2.001
Length SE - 1. 4. 0.
Lev Distance - 21. 18. 23.
UBS 4. 3. 3. 5.
BS 0. 0. 0. 0.
ILL 1. 1. 0. 1.
ILR 0. 0. 0. 1.
H 3. 2. 3. 3.
BL 0. 0. 0. 0.
BR 1. 0. 0. 1.
UN 0.175 0.259 0.268 0.212

Sequences

Field Description
UTR seq + 25 ggcauagcgccgacccucgcuccccgcccaggacccgaaugaaccuggagagcggATGATTGCTGAGCGCCTAGCACGAC
UTR dot + 25 (((…..)))…..((((((…..(((((………..))))).))))))…..(((((……)))))….
RS 1 seq AUAGAAGCAGGAAGCGUUUGACCUGCCGCCUUUAUAUGGGCACUUGGGCGGCAGCGAGCGAAUAGUGAGACCGACCUCAAA
RS 1 dot …………..((((((..(((((((((…………..)))))))))))))))…..((((……))))..
RS 2 seq UCUCCGCCGGCUGCGAUAAGGCACGGUUCAUAUCCCGGCCGCCUGGACCGUGCAUAGCUACUGGCGAGCCCGCCAGCAUCGA
RS 2 dot ….(((…..)))…..((((((((((………….))))))))))…….((((((….))))))……
RS 3 seq AUAUCCUAAAUGGGCAUUGAACUGCCACCUGUAUGUGGUCACCUGGGUGGCAGGGAGUCAGUGGUGAAACCGACUGAAAA
RS 3 dot …(((…..)))…….((((((((((..((….))..))))))))))….((((((((…))).)))))…

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