Detected as a riboswitch by 2 out of 20 classifiers
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5HSAA122216 Similarity: 0.988 Similarity: 0.987 Similarity: 0.986
UTR: 5HSAA122216
Gene: ZNF185
MFE: -13.948
ENS: 0.689
Length: 62.
Predicted Ligands:
fluoride - 16/20
unknown - 2/20
Mg2+ - 1/20
 RS: URS0000C31F6C_1150591
MFE: -19.825
Ligand: fluoride
Species: Mycobacterium xenopi RIVM700367 Fluoride riboswitch
 RS: URS0000CF85F4_2043167
MFE: -14.346
Ligand: fluoride
Species: Syntrophobacter sp. SbD1 crcB
 RS: URS0000D6B45F_1144340
MFE: -18.837
Ligand: unknown
Species: Pseudomonas sp. GM84 nhaA-I RNA
image of 5prime UTR secondary structure image of the secondary structure of the first Riboswitch match image of the secondary structure of the second Riboswitch match image of the secondary structure of the third Riboswitch match
circular plot of the 5prime UTR base pairs circular plot of the 5prime UTR base pairs compared with the first Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the second Riboswitch base pairs circular plot of the 5prime UTR base pairs compared with the third Riboswitch base pairs
line plot comparing the structural features of the 5prime UTR with its first riboswitch match line plot comparing the structural features of the 5prime UTR with its second riboswitch match line plot comparing the structural features of the 5prime UTR with its third riboswitch match
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heatmap comparing sequence features of the 5prime UTR and top three riboswitch matches
Heatmap of base pair probabilities for 1000 computational NUPACK foldings of the 5prime UTR
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon unbound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR that leave the start codon bound
Heatmap of base pair probabilities for computational NUPACK foldings of the 5prime UTR with the bound and unbound conformers overlaid
ML ensemble output for the 5prime UTR

Information

  5’UTR RS match 1 RS match 2 RS match 3
Link - RNAcentral RNAcentral RNAcentral
ID 5HSAA122216 URS0000C31F6C_1150591 URS0000CF85F4_2043167 URS0000D6B45F_1144340
Length 62. 61. 62. 63.
Similarity - 0.988 0.987 0.986
Ensemble Norm 0.689 - - -
MFE -13.948 -19.825 -14.346 -18.837
Ligands - fluoride fluoride unknown
Gene ZNF185 - - -
Downstream protein Genecard - - -

Similarity metrics

  5’UTR RS match 1 RS match 2 RS match 3
Struct SE - 7. 9.001 6.002
Length SE - 1. 0. 1.
Lev Distance - 13. 15. 16.
UBS 6. 5. 4. 5.
BS 0. 0. 0. 0.
ILL 3. 1. 1. 1.
ILR 2. 1. 1. 2.
H 2. 2. 2. 2.
BL 1. 1. 1. 2.
BR 1. 2. 1. 1.
UN 0.145 0.131 0.177 0.095

Sequences

Field Description
UTR seq + 25 cugaaucaagugagaggagagcugcggagcaaucaccATGGCCGCCCGGGACGAGCTCGGCC
UTR dot + 25 ………(((.(..((..(((….)))..)).))))(((((..(…….)..)))))
RS 1 seq GUUGACGUUGGCGAUGAAGCUCGCCUUGAUUGCCGCACCGGCUGAUGGCUUCUACCGCGUG
RS 1 dot ……..(((((((.(((…..))).)))))))((((((..((…..))..))).)))
RS 2 seq AUAUCCAGUGGUGAUGGAGUCCACCCACGACCGCCUUUUCGGCUGAUGACCCCUACCCGAGC
RS 2 dot …….(((((..(((…….)))..)))))…(((((.((……..)).))))).
RS 3 seq GGGUGCUAGCUGCAUGAAGCAGUGAUGCAGGUUAAACAGCUACGCAGGUCGGGCCGCCUUGCG
RS 3 dot ……((((((..(((.(((….)))…)))..))))))((((((.((…)).))))))

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